Endocrine Abstracts

Contexte: Acromegaly is a rare disease, usually caused by hypersecretion of growth hormone (GH) by a pituitary adenoma and very rarely by ectopic secretion of GHRH. It remains a serious disease reduces life expectancy because of its cardiovascular and metabolic impact.Objective: The objective of this study is to report the glycemic profile in patients followed for acromegaly in the endocrinologic center of CHU Med VI of Marrakech.P...

Contexte: Kallmann syndrome is a rare genetic disease which can affect both men and women. It combines hypogonadotropic hypogonadism which characterised by a failure to start or to fully complete puberty naturally; olfactory disorders such hyposmia or anosmia, impaired color vision, deafness, unilateral or bilateral renal aplasia and midline anomalies.Objective: We report a case of this rare syndrome, responsible of delayed puberty view of infertility.</...

Introduction: Growth hormone deficiency is a rare cause of stunting; its diagnosis is often delayed by severe growth retardation; confirmed by non-response to GH stimulation tests (insulin and glucagon-propranolol test). The absence of early diagnosis and treatment can lead to severe growth retardation. We propose to determine the prevalence of different etiologies of growth hormone deficiency in patients followed for a saturo-weight delay at the Arrazi Hospital, Medical Unive...

Introduction: Necrosis of the nasal pyramid is mainly of traumatic origin, among the other possible causes, those induced by systemic diseases, in particular Wegener’s granulomatosis…We report a case of necrosis of the nasal pyramid secondary to prolonged intubation in a type 1 diabetic.Observation: Patient T.T, 28 years old, followed for a poorly balanced type 1 diabetes, admitted to a blood clot in a table of diabetic ketoacidosis. The patie...

Introduction: Neurofibromatosis type 1 (NF1) is the most common autosomal dominant disease. The endocrine manifestations of NF1 are represented by pubertal abnormalities and pheochromocytoma. We report a case.Observation: Mr. G.A, age 28, consulling for a grade 2 HTA evolving for 3 years. The anamnesis notes paroxysmal crises made of Ménard triad. The exam notes a correct blood pressure, 18 coffee latte tasks, lentiginous tasks. Two neurofibromas of...

Introduction: Impetigo herpetiformis is a rare dermatological disorder, mimicking generalized pustular psoriasis. It is characterized by a generalized erythema-pustular eruption accompanied by fever. Its etiopathogenesis is poorly coded but triggers have been identified such as hypocalcemia in more than half of cases and pregnancy. We report a case of severe hypocalcemia secondary to hypoparathyroidism revealed by impetigo herpetiformis.Case report: Fort...

Introduction: The prison environment is a space that involves certain restrictions on prisoners. The diabetic subject requires, however, special attention. The aim of this work is to evaluate the impact of this medium on the glycemic balance and the metabolic profile.Patients and method: Descriptive cross-sectional study carried out on a health campaign day in a penitentiary center, in the men’s sector, and concerned patients with known diabetes fro...

Introduction: Somatotropic adenomas are clinically expressed either by acromegaly or by gigantism according to age of onset. Several histological types are involved. Immunohistochemistry provides conclusive evidence that significant diversity exists between growth hormone secreting (GH) tumors in excess. We report three observations of a particular histological type: mammosomatotropic adenoma.Observation 1: Mrs. M.H., aged 56, hypertensive for 10 years, ...

Introduction: Somatotropic adenomas are classically a source of hypersecretion of GH and consequently of IGF1 responsible for the clinical signs of acromegaly. Rarely, these adenomas remain ‘silent’, without any obvious clinical manifestation. They can then be detected on the basis of a routine determination of growth hormone under oral glucose tolerance test (GH/OGTT) and insulin growth factor 1 (IGF1) or be diagnosed only to immunohistochemical study as is the case...

Introduction: Angiosarcoma is a highly malignant tumor, very rare and even more so when it comes to a thyroid localization. It is characterized morphologically by its vascular differentiation and cytological polymorphism. The objective of this study is to report a case of this entity with its evolution in the postoperative period.Observation: patient of 54-year-oldm, with no pathological history. Operated (total thyroidectomy) for compressive multihetero...